Description

(S(R))-N-[(S)-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]-2-methyl-2-propanesulfinamide is a sophisticated chiral ligand and organocatalyst essential for asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, critical for producing single-isomer intermediates in pharmaceutical and fine chemical research. This compound is primarily needed by R&D chemists and process development scientists working on the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and other high-value chiral molecules.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and allylic substitution.
• As an organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond formation.
• Critical reagent in the research and development of novel pharmaceutical candidates, particularly for creating stereogenic centers.
• Use in process chemistry for scaling up the production of enantiomerically pure intermediates.
• Application in academic research for developing new methodologies in asymmetric synthesis.
• Potential use in the synthesis of specialty chemicals and advanced materials requiring precise stereochemical control.

Basic Information

Item	Details
Product Name	(S(R))-N-[(S)-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]-2-methyl-2-propanesulfinamide
CAS No.	2162939-87-7
Molecular Formula	C42H38NO2PS
Molecular Weight	651.80 g/mol
Synonyms	XantPhos Sulfinamide Ligand; (S,S)-DTBM-SEGPHOS Sulfinamide Derivative; Chiral Xantphos-based Sulfinamide; tert-Butanesulfinamide Xantphos Ligand; Asymmetric Synthesis Ligand 2162939-87-7; N-[(S)-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]-2-methyl-2-propanesulfinamide (S(R))-isomer
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized by advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing HPLC purity, chiral HPLC analysis, and NMR data are available upon request. We adhere to strict internal quality protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.