Description

[S(R)]-n-[(R)-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl](4-Methoxyphenyl)Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral ligand and synthetic intermediate, specifically designed for asymmetric catalysis and complex organic synthesis. Its value lies in the precise stereochemical control it imparts, enabling the production of enantiomerically pure compounds critical for advanced pharmaceutical and agrochemical research. This high-purity chemical is essential for R&D chemists and process development scientists working in pharmaceutical development, fine chemical synthesis, and materials science.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate: Key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Methodology Development: Used in academic and industrial research to develop new stereoselective synthetic routes.
• Agrochemical Synthesis: Intermediate for creating chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Fine Chemical Production: Enables the synthesis of specialty chemicals and flavors/fragrances requiring high enantiomeric purity.
• Material Science Research: Potential precursor for chiral polymers or advanced functional materials.

Basic Information

Product Name	[S(R)]-n-[(R)-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl](4-Methoxyphenyl)Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2160535-56-6
Molecular Formula	C41H40NO3PS
Molecular Weight	657.80 g/mol
Synonyms	(R)-DTBM-SEGPHOS Sulfinamide; (R)-5-(Diphenylphosphino)-4'-(4-methoxyphenyl)-9,9-dimethyl-9H-xanthene Sulfinamide; (R)-Xantphos Sulfinamide Derivative; Chiral Sulfinamide-Phosphine Hybrid Ligand; (R)-[5-(Diphenylphosphino)-9,9-dimethylxanthen-4-yl](4-methoxyphenyl)methyl]-2-methylpropane-2-sulfinamide; Asymmetric Sulfinamide Ligand; SEGPHOS-type Sulfinamide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of [S(R)]-n-[(R)-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl](4-Methoxyphenyl)Methyl]-2-Methyl-2-Propanesulfinamide adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and full spectroscopic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.