Description

tert-Butyl n-(3-Carbamoylcyclobutyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a cyclobutyl scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics, including kinase inhibitors and other targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.
• Chemical Biology Probes: Utilized in the creation of tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	tert-Butyl n-(3-Carbamoylcyclobutyl)Carbamate
CAS No.	2143202-33-7
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	1-N-Boc-3-aminocyclobutanecarboxamide; tert-Butyl (3-carbamoylcyclobutyl)carbamate; 3-[(tert-Butoxycarbonyl)amino]cyclobutanecarboxamide; 1-(tert-Butoxycarbonylamino)cyclobutane-3-carboxamide; Boc-3-Aminocyclobutanecarboxamide; (3-Carbamoylcyclobutyl)carbamic acid tert-butyl ester; Cyclobutanecarboxamide, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-; BOC-ACBCA
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(3-Carbamoylcyclobutyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.