Description

Potassium Trifluoro(3-Fluorobenzyl)Borate is a specialized organoboron reagent, specifically a potassium trifluoroborate salt. This compound is valued for its enhanced stability and handling properties compared to traditional boronic acids, making it a crucial building block in modern synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for advanced cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing fluorinated biaryl and heteroaryl motifs in active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Research & Development: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Material Science: Serves as a precursor for creating fluorinated organic electronic materials, including polymers and small molecules for OLEDs and semiconductors.
• Medicinal Chemistry: Enables efficient parallel and combinatorial synthesis for drug discovery libraries, allowing for the rapid exploration of structure-activity relationships (SAR).
• Process Chemistry & Scale-up: Its improved stability makes it suitable for developing robust and scalable manufacturing routes for fluorinated target molecules.
• Academic Research: A valuable tool in methodological studies for developing new catalytic systems and synthetic transformations involving organoboron species.

Basic Information

Product Name	Potassium Trifluoro(3-Fluorobenzyl)Borate
CAS No.	2126821-95-0
Molecular Formula	C7H6BF4K
Molecular Weight	207.03 g/mol
Synonyms	Potassium (3-Fluorobenzyl)trifluoroborate; (3-Fluorobenzyl)trifluoroboronic Acid Potassium Salt; Potassium Trifluoro(3-fluorophenylmethyl)borate; 3-Fluorobenzyltrifluoroborate Potassium Salt; Potassium 3-Fluorobenzyltrifluoroboronate; K-3-Fluorobenzyltrifluoroborate; (3-Fluorobenzyl)BF3K
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(3-Fluorobenzyl)Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
NMR Purity (1H, 19F)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.