Description

[(1-Ethynylcyclopropyl)Methyl]Benzene is a specialized organic building block featuring a unique combination of a benzene ring, a cyclopropyl group, and a terminal alkyne moiety. This molecular architecture makes it a valuable intermediate for advanced organic synthesis, particularly in the development of novel pharmaceuticals and functional materials. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring rigid, three-dimensional cyclopropyl scaffolds.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides, where the cyclopropane ring can impart specific biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the creation of advanced polymers and resins with tailored thermal or mechanical properties.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes, leveraging the reactivity of the alkyne group for click chemistry applications.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	[(1-Ethynylcyclopropyl)Methyl]Benzene
CAS No.	2126160-12-9
Molecular Formula	C12H12
Molecular Weight	156.22 g/mol
Synonyms	1-[(1-Ethynylcyclopropyl)methyl]benzene; Benzene, [(1-ethynylcyclopropyl)methyl]-; (1-Ethynylcyclopropyl)methylbenzene; α-Cyclopropylbenzeneacetylen; (Cyclopropylethynylmethyl)benzene; 1-Ethynyl-1-(phenylmethyl)cyclopropane
EINECS	Contact for details

Quality Control

Our [(1-Ethynylcyclopropyl)Methyl]Benzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.