Description

Do3A-Serotonin is a specialized bifunctional chelating agent designed for the conjugation of biomolecules to radionuclides for diagnostic and therapeutic applications. This compound matters because it provides a stable, high-affinity link between targeting vectors and metallic isotopes, which is critical for the efficacy and safety of radiopharmaceuticals. It is primarily needed by researchers and manufacturers in the fields of nuclear medicine, molecular imaging, and targeted radiotherapy for developing next-generation theranostic agents.

Application

• Radiopharmaceutical Precursor: Serves as a key intermediate in the synthesis of radiolabeled compounds for Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT).
• Theranostic Agent Development: Enables the creation of molecules that combine diagnostic imaging and targeted radionuclide therapy in a single platform.
• Bioconjugation Chemistry: Used to attach metallic radionuclides (e.g., Gallium-68, Lutetium-177, Copper-64) to peptides, antibodies, or other targeting moieties.
• Research & Development: A vital tool in academic and industrial labs for investigating new receptor-targeted imaging and treatment strategies.
• Preclinical Studies: Employed in the development and evaluation of novel radiopharmaceutical candidates in animal models.

Basic Information

Product Name	Do3A-Serotonin
CAS No.	2125661-93-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,4,7-Tris(carboxymethyl)-10-(2-((5-hydroxy-1H-indol-3-yl)ethyl)-1,4,7,10-tetraazacyclododecane; DO3A-Serotonin conjugate; Serotonin-DO3A; H2DO3A-Serotonin; 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-(5-hydroxy-1H-indol-3-yl)ethyl] derivative
EINECS	Contact for details

Quality Control

Our Do3A-Serotonin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.