Description

(3-Chloro-5-Fluoro-2-Hydroxyphenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in its role as a key building block in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. This compound is critically needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its ability to form carbon-carbon bonds under mild conditions.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and sensors due to its boronic acid functionality's affinity for diols.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CROs serving the global life sciences market.

Basic Information

Item	Detail
Product Name	(3-Chloro-5-Fluoro-2-Hydroxyphenyl)Boronic Acid
CAS No.	2121515-30-6
Molecular Formula	C6H5BClFO3
Molecular Weight	189.37 g/mol
Synonyms	2-Hydroxy-3-chloro-5-fluorobenzeneboronic acid; (3-Chloro-5-fluoro-2-hydroxyphenyl)boronic acid; 3-Chloro-5-fluoro-2-hydroxybenzeneboronic acid; Boronic acid, B-(3-chloro-5-fluoro-2-hydroxyphenyl)-; CAS 2121515-30-6
EINECS	Contact for details

Quality Control

Our (3-Chloro-5-Fluoro-2-Hydroxyphenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.