Description

3,5-Dichloro-2-Fluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound is critical as a key building block in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the dichloro-fluorophenyl moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis or as a scaffold for creating boron-based sensor molecules.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CMOs (Contract Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3,5-Dichloro-2-Fluorophenylboronic Acid Pinacol Ester
CAS No.	2121515-08-8
Molecular Formula	C12H14BCl2FO2
Molecular Weight	291.96 g/mol
Synonyms	2-Fluoro-3,5-dichlorophenylboronic acid pinacol ester; (3,5-Dichloro-2-fluorophenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(3,5-dichloro-2-fluorophenyl)-1,3,2-dioxaborolane; Pinacol (3,5-dichloro-2-fluorophenyl)boronate; 3,5-Dichloro-2-fluorobenzeneboronic acid pinacol ester; B-(3,5-Dichloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.