Description

2,5-Difluoro-4-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules with precise structural control. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional organic compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboron reagent for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery.
• Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing difluoromethoxy-substituted aromatic systems.
• Agrochemical Synthesis: Production of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic motifs.
• Ligand and Catalyst Development: Building block for creating specialized ligands used in catalysis and material science.
• Organic Electronic Materials: Research and development of organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Synthesis of tagged molecules for studying biological processes and target engagement.

Basic Information

Item	Detail
Product Name	2,5-Difluoro-4-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	2121515-03-3
Molecular Formula	C₁₃H₁₇BF₂O₃
Molecular Weight	270.08 g/mol
Synonyms	2,5-Difluoro-4-methoxyphenylboronic acid pinacol ester; 4-Methoxy-2,5-difluorophenylboronic acid pinacol ester; (2,5-Difluoro-4-methoxyphenyl)boronic acid pinacol ester; 2,5-Difluoro-4-methoxybenzeneboronic acid pinacol ester; 2-(2,5-Difluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2121515-03-3; Pinacol 2,5-difluoro-4-methoxyphenylboronate
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.