Description

2-Chloro-3-Fluoro-4-Formylphenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both halogen and formyl substituents, makes it an indispensable reagent for constructing complex molecular architectures via cross-coupling reactions. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic ring for bioactivity.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where its boronic acid group enables precise molecular assembly.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of activity-based probes and sensors.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel bidentate ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Item	Details
Product Name	2-Chloro-3-Fluoro-4-Formylphenylboronic Acid
CAS No.	2121514-97-2
Molecular Formula	C7H5BClFO3
Molecular Weight	201.38 g/mol
Synonyms	2-Chloro-3-fluoro-4-formylbenzeneboronic acid; (2-Chloro-3-fluoro-4-formylphenyl)boronic acid; 4-Borono-2-chloro-3-fluorobenzaldehyde; 2-Chloro-3-fluoro-4-carboxaldehydephenylboronic acid; B-(2-Chloro-3-fluoro-4-formylphenyl)boronic acid; 2121514-97-2; AKOS026713065
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Fluoro-4-Formylphenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.