Description

2-Chloro-4-Fluoro-6-Methylphenylboronic Acid CAS NO 2121514-96-1 is a high-purity, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for biochemical research and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	2-Chloro-4-Fluoro-6-Methylphenylboronic Acid
CAS No.	2121514-96-1
Molecular Formula	C7H7BClFO2
Molecular Weight	187.39 g/mol
Synonyms	(2-Chloro-4-fluoro-6-methylphenyl)boronic acid; 2-Chloro-4-fluoro-6-methylbenzeneboronic acid; B-(2-Chloro-4-fluoro-6-methylphenyl)boronic acid; 2121514-96-1; 2-Chloro-4-fluoro-6-methylphenylboronic acid pinacol ester (common derivative); 2-Cl-4-F-6-MeC6H2B(OH)2
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluoro-6-Methylphenylboronic Acid is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR, and MS to verify identity, purity, and consistency. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.