Description

3,5-Difluoro-4-(Methylthio)Phenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound matters as a critical intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecules for advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds prevalent in pharmaceutical candidates.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic catalysts.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and probes for biological target identification.

Basic Information

Product Name	3,5-Difluoro-4-(Methylthio)Phenylboronic Acid Pinacol Ester
CAS No.	2121514-92-7
Molecular Formula	C₁₄H₁₉BF₂O₂S
Molecular Weight	300.17 g/mol
Synonyms	4-(Methylthio)-3,5-difluorophenylboronic acid pinacol ester; 3,5-Difluoro-4-(methylsulfanyl)benzeneboronic acid pinacol ester; 2-[3,5-Difluoro-4-(methylsulfanyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,5-Difluoro-4-methylthiophenylboronic acid pinacol ester; (3,5-Difluoro-4-(methylthio)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(Methylthio)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.