Description

3-[4-(Trifluoromethoxy)Phenyl]-Pyridine-5-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Item	Details
Product Name	3-[4-(Trifluoromethoxy)Phenyl]-Pyridine-5-Boronic Acid
CAS No.	2121514-15-4
Molecular Formula	C12H9BF3NO3
Molecular Weight	283.01 g/mol
Synonyms	5-(4-(Trifluoromethoxy)phenyl)pyridine-3-boronic acid; [5-(4-Trifluoromethoxy-phenyl)-pyridin-3-yl]-boronic acid; 3-Pyridineboronic acid, 5-[4-(trifluoromethoxy)phenyl]-; 3-(4-Trifluoromethoxyphenyl)-5-pyridinylboronic acid; Boronic acid, B-[5-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Every batch of 3-[4-(Trifluoromethoxy)Phenyl]-Pyridine-5-Boronic Acid is produced under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.