Description

7-Fluoro-1H-Indazole-4-Boronic Acid is a high-value boronic acid derivative and a key pharmaceutical intermediate. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds between aryl halides and boronic acids, enabling the construction of complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Potential monomer or precursor for creating advanced organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and activity-based protein profiling reagents.
• Contract Research & Development (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	7-Fluoro-1H-Indazole-4-Boronic Acid
CAS No.	2121513-84-4
Molecular Formula	C7H6BFN2O2
Molecular Weight	179.94 g/mol
Synonyms	7-Fluoro-1H-indazole-4-boronic acid; (7-Fluoro-1H-indazol-4-yl)boronic acid; 4-Borono-7-fluoro-1H-indazole; 7-Fluoro-4-indazoleboronic acid; 7-Fluoroindazole-4-boronic acid; B-(7-Fluoro-1H-indazol-4-yl)boronic acid; 2121513-84-4
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1H-Indazole-4-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.