Description

6-Fluoro-2-Hydroxy-3-Methylphenylboronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a boronic acid group and a fluorine substituent on a phenolic scaffold, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its utility extends to advanced material science for creating specialized polymers and ligands.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & Polymer Chemistry: Building block for synthesizing specialized ligands, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Liquid Crystal & OLED Material Production: Intermediate in the manufacture of fluorine-containing advanced electronic and display materials.
• Diagnostic Reagent Synthesis: Used in the development of biochemical probes and sensor materials.

Basic Information

Product Name	6-Fluoro-2-Hydroxy-3-Methylphenylboronic Acid
CAS No.	2121513-74-2
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(6-Fluoro-2-hydroxy-3-methylphenyl)boronic acid; 2-Borono-6-fluoro-3-methylphenol; 3-Methyl-6-fluoro-2-hydroxybenzeneboronic acid; 6-Fluoro-3-methyl-2-hydroxybenzeneboronic acid; 6-Fluoro-2-hydroxy-3-methylbenzeneboronic acid; Boronic acid, B-(6-fluoro-2-hydroxy-3-methylphenyl)-; CAS 2121513-74-2
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Hydroxy-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and hydrolysis. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.