Description

5-Chloro-2-Fluoro-4-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is specifically designed for chemists and manufacturers engaged in the development of complex molecules, particularly in the life sciences and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for constructing molecular libraries in medicinal chemistry and for exploring new synthetic pathways in academic and industrial R&D.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	2121513-64-0
Molecular Formula	C₁₃H₁₇BClFO₃
Molecular Weight	286.53 g/mol
Synonyms	5-Chloro-2-fluoro-4-methoxyphenylboronic acid pinacol ester; (5-Chloro-2-fluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(5-Chloro-2-fluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chloro-2-fluoro-4-methoxybenzeneboronic acid pinacol ester; Boronic acid, B-(5-chloro-2-fluoro-4-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.