Description

2-Ethoxy-6-Fluoro-4-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated and ethoxy-substituted aromatic systems.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis or as a scaffold for catalyst design.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes, leveraging the boronic acid group's affinity for diols.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis organizations (CSOs) and CROs serving the global life sciences industry.

Basic Information

Product Name	2-Ethoxy-6-Fluoro-4-Methylphenylboronic Acid
CAS No.	2121513-45-7
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(2-Ethoxy-6-fluoro-4-methylphenyl)boronic acid; 2-Ethoxy-6-fluoro-p-tolylboronic acid; 4-Methyl-2-ethoxy-6-fluorophenylboronic acid; B-(2-Ethoxy-6-fluoro-4-methylphenyl)boronic acid; 2-Fluoro-6-ethoxy-4-methylbenzeneboronic acid; Boronic acid, B-(2-ethoxy-6-fluoro-4-methylphenyl)-; CAS 2121513-45-7
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-6-Fluoro-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.