Description

5-Bromo-3-(4-Fluorophenyl)Aminocarbonylphenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling its use as a key intermediate in the construction of complex molecules via cross-coupling reactions. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the boronic acid moiety for creating complex bioactive molecules.
• Material Science: Serves as a monomer or linker in the synthesis of organic electronic materials, such as polymers for OLEDs and sensors.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and affinity ligands for studying protein function and enzyme inhibition.
• Catalyst Ligand Synthesis: Acts as a starting material for creating specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the bespoke production of client-specified complex organic molecules.

Basic Information

Product Name	5-Bromo-3-(4-Fluorophenyl)Aminocarbonylphenylboronic Acid
CAS No.	2121513-21-9
Molecular Formula	C13H10BBrFNO3
Molecular Weight	337.94 g/mol
Synonyms	[5-Bromo-3-[(4-fluorophenyl)carbamoyl]phenyl]boronic acid; 3-Amino-5-bromo-N-(4-fluorophenyl)benzamide boronic acid; 5-Bromo-N-(4-fluorophenyl)-3-(dihydroxyboryl)benzamide; 2121513-21-9; Boronic acid, B-[5-bromo-3-[[(4-fluorophenyl)amino]carbonyl]phenyl]-; 5-Bromo-3-((4-fluorophenyl)carbamoyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-(4-Fluorophenyl)Aminocarbonylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.