Description

4-Fluoro-3-(Methylthio)Phenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures critical in modern organic synthesis. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, particularly those containing fluorinated and sulfur-substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, via cross-coupling polymerization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target engagement.
• Academic & Industrial R&D: A versatile reagent for methodological development and scale-up synthesis in research laboratories.

Basic Information

Product Name	4-Fluoro-3-(Methylthio)Phenylboronic Acid Pinacol Ester
CAS No.	2121513-04-8
Molecular Formula	C₁₃H₁₈BFO₂S
Molecular Weight	268.16 g/mol
Synonyms	4-Fluoro-3-(methylthio)benzeneboronic acid pinacol ester; (4-Fluoro-3-(methylthio)phenyl)boronic acid pinacol ester; 2-(4-Fluoro-3-(methylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methylthio-4-fluorophenylboronic acid pinacol ester; Pinacol 4-Fluoro-3-(methylthio)phenylboronate; B-[4-Fluoro-3-(methylthio)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2121513-04-8
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Methylthio)Phenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with rigorous R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.