Description

5-Bromo-2,3-Difluoro-4-Methylphenylboronic Acid CAS NO 2121513-00-4 is a high-purity, multi-functional boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, crop protection, and organic electronic development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing complex, halogenated biaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated phenyl motifs for enhanced activity.
• Material Science Research: Serves as a building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its boronic acid functionality and halogen substituents.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and sensors that utilize boronic acid-diol interactions for detection and imaging applications.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl compounds with high efficiency and selectivity.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Bromo-2,3-Difluoro-4-Methylphenylboronic Acid
CAS No.	2121513-00-4
Molecular Formula	C7H6BBrF2O2
Molecular Weight	248.84 g/mol
Synonyms	(5-Bromo-2,3-difluoro-4-methylphenyl)boronic acid; 2,3-Difluoro-5-bromo-4-methylbenzeneboronic acid; 4-Borono-2-bromo-1,3-difluoro-5-methylbenzene; 5-Bromo-2,3-difluoro-p-tolylboronic acid; B-(5-Bromo-2,3-difluoro-4-methylphenyl)boronic acid; 2121513-00-4; Boronic acid, B-(5-bromo-2,3-difluoro-4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Difluoro-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.