Description

2,6-Difluoro-3-Formylphenylboronic Acid Pinacol Ester is a high-value, multifunctional boronic ester building block designed for advanced organic synthesis. This compound matters for its unique combination of a protected boronic acid group and a reactive formyl group, enabling precise cross-coupling and subsequent functionalization in a single molecule. Pharmaceutical, agrochemical, and materials science researchers need it for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in fluorinated bioactive compounds.
• Agrochemical Synthesis: Used in creating advanced, fluorinated pesticides and herbicides with enhanced stability and activity.
• Liquid Crystal & OLED Material Precursor: Serves as a critical intermediate for synthesizing fluorinated aromatic cores used in electronic display materials.
• Polymer & Resin Modification: Enables the introduction of boronic ester and aldehyde functionalities into polymer backbones for specialty materials.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and sensors that leverage boronic acid-diol interactions.
• Academic & Contract Research: Essential for methodological development and library synthesis in research institutions and CROs.

Basic Information

Product Name	2,6-Difluoro-3-Formylphenylboronic Acid Pinacol Ester
CAS No.	2121512-61-4
Molecular Formula	C₁₄H₁₇BF₂O₃
Molecular Weight	282.10 g/mol
Synonyms	2,6-Difluoro-3-formylbenzeneboronic acid pinacol ester; (2,6-Difluoro-3-formylphenyl)boronic acid pinacol ester; 3-Formyl-2,6-difluorophenylboronic acid pinacol ester; Pinacol (2,6-difluoro-3-formylphenyl)boronate; 2-(2,6-Difluoro-3-formylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2121512-61-4
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Formylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.