Description

2-Fluoro-3-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid Pinacol Ester is a sophisticated, high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for complex cross-coupling reactions, which are fundamental to constructing advanced molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where it facilitates the development of novel active ingredients and functional materials. The CAS number for this compound is 2121512-58-9.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex, fluorinated biaryl structures found in drug discovery and development.
• Agrochemical Synthesis: Used to create novel, fluorinated active ingredients for crop protection agents, leveraging the stability of the pinacol ester for multi-step synthesis.
• Materials Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors, where precise molecular control is required.
• Chemical Biology Probes: Enables the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-fidelity boronic acid derivatives.

Basic Information

Product Name	2-Fluoro-3-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid Pinacol Ester
CAS No.	2121512-58-9
Molecular Formula	C15H21BFNO3
Molecular Weight	293.14 g/mol
Synonyms	2-Fluoro-3-(N,N-dimethylcarbamoyl)phenylboronic acid pinacol ester; (2-Fluoro-3-(dimethylcarbamoyl)phenyl)boronic acid pinacol ester; 3-Carbamoyl-2-fluorophenylboronic acid pinacol ester; Pinacol [2-fluoro-3-(N,N-dimethylaminocarbonyl)phenyl]boronate; B-[2-Fluoro-3-[(dimethylamino)carbonyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2121512-58-9; Boronic acid, B-[2-fluoro-3-[(dimethylamino)carbonyl]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid Pinacol Ester is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.