Description

5-Chloro-2-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl and chloro-substituted aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the specific halogenated aromatic motif is required for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-Chloro-2-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	2121512-57-8
Molecular Formula	C₁₃H₁₅BClF₃O₂
Molecular Weight	306.52 g/mol
Synonyms	5-Chloro-2-(trifluoromethyl)benzeneboronic acid pinacol ester; (5-Chloro-2-(trifluoromethyl)phenyl)boronic acid pinacol ester; 2-Chloro-α,α,α-trifluoro-p-tolylboronic acid pinacol ester; 5-Chloro-α,α,α-trifluoro-o-tolylboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[5-chloro-2-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane; CAS 2121512-57-8
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.