Description

3-Fluoro-2-Methyl-6-(Methylthio)Phenylboronic Acid Pinacol Ester is a high-purity, advanced boronic ester building block crucial for modern synthetic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing complex biaryl or heterobiaryl structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific fluorinated and thioether motifs for enhanced activity.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling polymerization.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological pathways and diagnostic applications.
• Catalyst & Ligand Synthesis: Used to construct sophisticated ligand frameworks for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	3-Fluoro-2-Methyl-6-(Methylthio)Phenylboronic Acid Pinacol Ester
CAS No.	2121512-53-4
Molecular Formula	C14H20BFO2S
Molecular Weight	282.18 g/mol
Synonyms	(3-Fluoro-2-methyl-6-(methylthio)phenyl)boronic acid pinacol ester; 2-(3-Fluoro-2-methyl-6-(methylsulfanyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Fluoro-2-methyl-6-(methylthio)benzeneboronic acid pinacol ester; Pinacol [3-fluoro-2-methyl-6-(methylthio)phenyl]boronate; Boronic acid, B-[3-fluoro-2-methyl-6-(methylthio)phenyl]-, 1,1-dimethylethyl ester (9CI); 2121512-53-4; Fluoromethylthiophenylboronic ester
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methyl-6-(Methylthio)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.