Description

3-(Trifluoromethyl)Biphenyl-4-Ylboronic Acid CAS NO 2121512-52-3 is a high-purity organoboron compound, specifically a boronic acid derivative, that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecular architectures through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality reagents for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing biphenyl and trifluoromethyl motifs common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Development: Serves as a building block for creating organic electronic materials, including charge-transport layers and emissive compounds for displays and lighting.
• Polymer & Specialty Chemical Manufacturing: Employed to introduce functional biphenyl units into polymers and specialty chemicals to modify physical properties like thermal stability and solubility.
• Chemical Research & Process Development: An essential reagent for academic and industrial R&D laboratories exploring new synthetic methodologies and scaling up production processes.

Basic Information

Product Name	3-(Trifluoromethyl)Biphenyl-4-Ylboronic Acid
CAS No.	2121512-52-3
Molecular Formula	C13H10BF3O2
Molecular Weight	266.03 g/mol
Synonyms	[4-(3-Trifluoromethylphenyl)phenyl]boronic acid; 3'-Trifluoromethyl[1,1'-biphenyl]-4-boronic acid; 4-(3-(Trifluoromethyl)phenyl)benzeneboronic acid; 3-(Trifluoromethyl)-4-biphenylboronic Acid; 3-Trifluoromethylbiphenyl-4-boronic Acid; B-[4-(3-Trifluoromethylphenyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Biphenyl-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.