Description

2-Fluoro-5-(Methylthio)Phenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, particularly in the synthesis of complex molecules for advanced materials and life sciences. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to innovate and scale novel compounds.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific fluorinated and thioether motifs.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and semiconductors, where the fluorine and sulfur groups modulate electronic properties.
• Chemical Biology & Probe Development: Serves as a versatile handle for creating fluorescent tags, molecular probes, and PROTACs for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries for drug discovery campaigns.

Basic Information

Product Name	2-Fluoro-5-(Methylthio)Phenylboronic Acid
CAS No.	2121512-51-2
Molecular Formula	C7H8BFO2S
Molecular Weight	185.99 g/mol
Synonyms	(2-Fluoro-5-(methylthio)phenyl)boronic acid; 2-Fluoro-5-methylsulfanylbenzeneboronic acid; 5-Methylthio-2-fluorophenylboronic acid; B-[2-Fluoro-5-(methylthio)phenyl]boronic acid; 2-Fluoro-5-(methylmercapto)benzeneboronic acid; 2121512-51-2; Boronic acid, B-[2-fluoro-5-(methylthio)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Methylthio)Phenylboronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Our standard quality commitment includes comprehensive analysis by HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.