Description

6-Bromo-2,4-Fifluoro-3-Formylphenylboronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. This compound matters because it combines a reactive formyl group, halogen substituents, and a protected boronic acid moiety, enabling precise and complex molecular construction. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or building block for creating functional polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the development of tagged molecules and activity-based probes for studying biological pathways.
• Ligand and Catalyst Development: Useful for synthesizing novel bidentate or tridentate ligands for transition metal catalysis.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	6-Bromo-2,4-Fifluoro-3-Formylphenylboronic Acid Pinacol Ester
CAS No.	2121512-44-3
Molecular Formula	C₁₃H₁₄BBrF₂O₃
Molecular Weight	347.96 g/mol
Synonyms	(6-Bromo-2,4-difluoro-3-formylphenyl)boronic acid pinacol ester; 2-(6-Bromo-2,4-difluoro-3-formylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Bromo-2,4-difluoro-3-formylbenzeneboronic acid pinacol ester; Pinacol (6-Bromo-2,4-difluoro-3-formylphenyl)boronate; Boronic acid, B-(6-bromo-2,4-difluoro-3-formylphenyl)-, 1,1,1',1'-tetramethyl-2,2'-bi-1,3,2-dioxaborolane-4,4'-diyl ester; CAS 2121512-44-3
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,4-Fifluoro-3-Formylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.