Description

2,3-Dimethoxy-4-Fluorophenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated and methoxylated biaryl scaffolds found in drug candidates.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides with enhanced properties through targeted molecular modification.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 2,3-dimethoxy-4-fluorophenyl moiety into more complex molecules in academic and industrial R&D.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,3-Dimethoxy-4-Fluorophenylboronic Acid Pinacol Ester
CAS No.	2121512-21-6
Molecular Formula	C14H20BFO4
Molecular Weight	282.12 g/mol
Synonyms	2,3-Dimethoxy-4-fluorophenylboronic acid pinacol ester; 4-Fluoro-2,3-dimethoxyphenylboronic acid pinacol ester; (2,3-Dimethoxy-4-fluorophenyl)boronic acid pinacol ester; Pinacol (2,3-dimethoxy-4-fluorophenyl)boronate; 2,3-Dimethoxy-4-fluorobenzeneboronic acid pinacol ester; B-(2,3-Dimethoxy-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2,3-Dimethoxy-4-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.