Description

2,4-Dibromo-6-Fluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound matters as a critical intermediate in modern cross-coupling reactions, enabling the precise construction of complex fluorinated and brominated aromatic systems. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing the 2,4-dibromo-6-fluorophenyl moiety into complex molecules, enabling carbon-carbon bond formation under mild conditions.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly those requiring specific halogenated aromatic scaffolds for bioactivity.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Used to create monomers and precursors for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological processes and target engagement.

Basic Information

Product Name	2,4-Dibromo-6-Fluorophenylboronic Acid Pinacol Ester
CAS No.	2121512-09-0
Molecular Formula	C₁₂H₁₄BBr₂FO₂
Molecular Weight	379.86 g/mol
Synonyms	2,4-Dibromo-6-fluorophenylboronic acid pinacol ester; (2,4-Dibromo-6-fluorophenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2,4-dibromo-6-fluorophenyl)-1,3,2-dioxaborolane; 2-(2,4-Dibromo-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2,4-dibromo-6-fluorophenyl)boronate; B-(2,4-Dibromo-6-fluorophenyl)boronic acid pinacol ester; 2,4-Dibromo-6-fluorobenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-6-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.