Description

3-Bromo-6-Fluoro-2-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected boronic acid building block, enabling efficient cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for constructing complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs or charge-transport materials, where the bromo and fluoro substituents fine-tune electronic properties.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds, offering advantages in stability and handling over the corresponding boronic acid.
• Chemical Library Development: Serves as a versatile scaffold for generating diverse compound libraries in medicinal chemistry and drug discovery programs.
• Ligand and Catalyst Preparation: Can be used to synthesize sophisticated ligands for catalysis or as a precursor for functionalized materials.

Basic Information

Item	Details
Product Name	3-Bromo-6-Fluoro-2-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	2121511-98-4
Molecular Formula	C₁₃H₁₇BBrFO₃
Molecular Weight	329.99 g/mol
Synonyms	3-Bromo-6-fluoro-2-methoxyphenylboronic acid pinacol ester; 2-(3-Bromo-6-fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Bromo-6-fluoro-2-methoxyphenyl)boronic acid pinacol ester; Pinacol (3-bromo-6-fluoro-2-methoxyphenyl)boronate; 3-Bromo-6-fluoro-2-methoxybenzeneboronic acid pinacol ester; Boronic acid, B-(3-bromo-6-fluoro-2-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI); CAS 2121511-98-4
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Fluoro-2-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.