Description

(4-Fluoro-1H-Indazol-6-Yl)Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and a crucial building block in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecules through versatile cross-coupling reactions, particularly Suzuki-Miyaura couplings. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who are developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Enables the formation of carbon-carbon bonds to attach complex aryl or heteroaryl groups, critical for constructing drug-like molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized in the design of bifunctional molecules for targeted protein degradation.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	(4-Fluoro-1H-Indazol-6-Yl)Boronic Acid Pinacol Ester
CAS No.	2121511-94-0
Molecular Formula	C₁₃H₁₆BFN₂O₂
Molecular Weight	262.09 g/mol
Synonyms	4-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-fluoro-1H-indazole; (4-Fluoro-1H-indazol-6-yl)boronic acid pinacol ester; 4-Fluoro-1H-indazole-6-boronic acid pinacol ester; B-(4-Fluoro-1H-indazol-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2121511-94-0; 4-Fluoro-6-(pinacolboranyl)-1H-indazole
EINECS	Contact for details

Quality Control

Our (4-Fluoro-1H-Indazol-6-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and ensures reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged procedures to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.