Description

3-Chloro-6-Fluoro-2-Methoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures efficiently. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Employed in the creation of organic electronic materials, including OLEDs and semiconductors, due to its ability to form stable carbon-boron bonds.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the construction of molecular probes and sensors for studying biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	3-Chloro-6-Fluoro-2-Methoxyphenylboronic Acid
CAS No.	2121511-91-7
Molecular Formula	C7H7BClFO3
Molecular Weight	203.39 g/mol
Synonyms	(3-Chloro-6-fluoro-2-methoxyphenyl)boronic acid; 2-Methoxy-3-chloro-6-fluorophenylboronic acid; 3-Chloro-6-fluoro-2-methoxybenzeneboronic acid; Boronic acid, B-(3-chloro-6-fluoro-2-methoxyphenyl)-; 2121511-91-7; 3-Chloro-6-fluoro-o-anisylboronic acid; 3-Chloro-6-fluoro-2-methoxy phenyl boronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-6-Fluoro-2-Methoxyphenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.