Description

3-Fluoro-2-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing fluorinated biaryl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the specific substitution pattern can influence biological activity and selectivity.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis or as a core structure in catalyst design.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes, leveraging the boronic acid group's affinity for diols.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	3-Fluoro-2-Isopropoxyphenylboronic Acid
CAS No.	2121511-87-1
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(3-Fluoro-2-isopropoxyphenyl)boronic Acid; 2-Isopropoxy-3-fluorophenylboronic Acid; 3-Fluoro-2-(1-methylethoxy)benzeneboronic Acid; Boronic acid, B-(3-fluoro-2-isopropoxyphenyl)-; 2121511-87-1; 3-Fluoro-2-isopropoxybenzeneboronic acid; 3-Fluoro-2-propan-2-yloxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Isopropoxyphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment. Our quality commitment supports applications in cGMP and non-GMP environments alike.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.