Description

2-Fluoro-6-(Methoxymethoxy)Phenylboronic Acid is a specialized boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionalization, featuring both a fluorine substituent and a protected hydroxyl group, which makes it a versatile and highly sought-after intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and medicinal chemistry.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Serves as a critical precursor in the development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes due to the reactivity of the boronic acid group.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis organizations (CSOs) and CDMOs serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-6-(Methoxymethoxy)Phenylboronic Acid
CAS No.	2121511-85-9
Molecular Formula	C9H12BFO4
Molecular Weight	213.99 g/mol
Synonyms	(2-Fluoro-6-(methoxymethoxy)phenyl)boronic acid; 2-Fluoro-6-MOM-phenylboronic Acid; [2-Fluoro-6-(methoxymethoxy)phenyl]boronic acid; B-[2-Fluoro-6-(methoxymethoxy)phenyl]boronic acid; 2-Fluoro-6-(MOMoxy)phenylboronic Acid; 2-Fluoro-6-(Methoxymethoxy)benzeneboronic Acid; (2-Fluoro-6-MOM-phenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Methoxymethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.