Description

3-(N,N-Dimethylamino)-5-Fluorophenylboronic Acid is a specialized organoboron compound featuring both a dimethylamino electron-donating group and a fluorine substituent on the aromatic ring. This unique bifunctional structure makes it a highly valuable building block for modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating advanced functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand & Catalyst Development: The boronic acid and amino groups allow it to be used in constructing sophisticated ligands for catalysis.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and sensors for studying biological processes.
• Academic & R&D: A versatile reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	3-(N,N-Dimethylamino)-5-Fluorophenylboronic Acid
CAS No.	2121511-70-2
Molecular Formula	C8H11BFNO2
Molecular Weight	182.99 g/mol
Synonyms	(3-(Dimethylamino)-5-fluorophenyl)boronic acid; 5-Fluoro-3-(dimethylamino)benzeneboronic acid; 3-Dimethylamino-5-fluorobenzeneboronic acid; B-[3-(Dimethylamino)-5-fluorophenyl]boronic acid; 3-Fluoro-5-(N,N-dimethylamino)phenylboronic acid; 2121511-70-2; 3-(Dimethylamino)-5-fluorophenylboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 3-(N,N-Dimethylamino)-5-Fluorophenylboronic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.