Description

5-Chloro-2-Fluoro-4-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for organic electronic materials used in displays and lighting.
• Polymer Chemistry: Facilitates the creation of specialty polymers and functional materials with tailored properties.
• Chemical Research & Development: Employed in academic and industrial R&D for method development and library synthesis in medicinal chemistry.
• Custom Synthesis: A vital starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Isopropoxyphenylboronic Acid
CAS No.	2121511-67-7
Molecular Formula	C9H11BClFO3
Molecular Weight	231.45 g/mol
Synonyms	(5-Chloro-2-fluoro-4-isopropoxyphenyl)boronic acid; 2-Fluoro-5-chloro-4-isopropoxybenzeneboronic acid; 4-Isopropoxy-5-chloro-2-fluorophenylboronic acid; Boronic acid, B-(5-chloro-2-fluoro-4-isopropoxyphenyl)-; 2121511-67-7; 5-Chloro-2-fluoro-4-(propan-2-yloxy)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.