Description

(5-Fluoro-2-Isopropoxypyridin-4-Yl)Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. Its core value lies in its role as a protected boronic acid derivative, offering enhanced stability and reactivity for critical carbon-carbon bond-forming reactions. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for complex synthesis, particularly in the creation of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for constructing biaryl and heterobiaryl structures central to many drug candidates and functional materials.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated pyridine motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated heterocyclic scaffolds.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Chemical Biology & Medicinal Chemistry: Facilitates the creation of molecular probes and libraries for drug discovery and target identification studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(5-Fluoro-2-Isopropoxypyridin-4-Yl)Boronic Acid Pinacol Ester
CAS No.	2121511-50-8
Molecular Formula	C15H23BFNO3
Molecular Weight	295.16 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-[5-fluoro-2-(propan-2-yloxy)pyridin-4-yl]-1,3,2-dioxaborolane; 2-(5-Fluoro-2-isopropoxypyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-Fluoro-2-Isopropoxy-4-pyridinyl)boronic Acid Pinacol Ester; 5-Fluoro-2-isopropoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boronic acid, B-[5-fluoro-2-[(1-methylethyl)oxy]-4-pyridinyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our (5-Fluoro-2-Isopropoxypyridin-4-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent lot-to-lot performance suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.