Description

2,3-Difluoro-6-isopropoxyphenylboronic acid is a high-value organoboron building block, specifically a substituted phenylboronic acid. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to synthesize complex, fluorinated aromatic target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated biaryl structures found in active pharmaceutical ingredients (APIs), leveraging the Suzuki-Miyaura cross-coupling reaction.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the difluoro and isopropoxy substituents confer specific biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands or functionalized materials used in catalysis and sensor technology.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, or organic electronic materials to modify electronic properties and stability.
• Custom Synthesis & Contract Manufacturing: Essential for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2,3-Difluoro-6-isopropoxyphenylboronic Acid
CAS No.	2121511-47-3
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(2,3-Difluoro-6-isopropoxyphenyl)boronic Acid; 2,3-Difluoro-6-(1-methylethoxy)benzeneboronic Acid; 2,3-Difluoro-6-isopropoxybenzeneboronic Acid; Boronic acid, B-(2,3-difluoro-6-isopropoxyphenyl)-; 2121511-47-3; 2,3-Difluoro-6-propan-2-yloxyphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.