Description

3-(n-Methylaminomethyl)-2-Fluorophenylboronic Acid is a specialized organoboron compound featuring a fluorinated phenyl ring and a methylaminomethyl side chain. This unique structure makes it a valuable high-purity building block for modern synthetic chemistry, particularly in cross-coupling reactions. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring fluorinated aromatic components.
• Material Science Research: Serves as a monomer or functionalization agent in the development of novel polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	3-(n-Methylaminomethyl)-2-Fluorophenylboronic Acid
CAS No.	2121511-43-9
Molecular Formula	C8H11BFNO2
Molecular Weight	182.99 g/mol
Synonyms	2-Fluoro-3-[(methylamino)methyl]benzeneboronic Acid; (2-Fluoro-3-((methylamino)methyl)phenyl)boronic Acid; 3-(Methylaminomethyl)-2-fluorobenzeneboronic Acid; B-(2-Fluoro-3-((methylamino)methyl)phenyl)boronic Acid; 2-Fluoro-3-(N-methylaminomethyl)phenylboronic Acid; 3-(Methylaminomethyl)-2-fluorophenylboronic Acid Pinacol Ester (common derivative); 2121511-43-9
EINECS	Contact for details

Quality Control

Our 3-(n-Methylaminomethyl)-2-Fluorophenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.