Description

2-Chloro-3,4-Difluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing complex biaryl structures.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific halogenated phenyl motifs for enhanced activity.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as polymers for OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-3,4-Difluorophenylboronic Acid
CAS No.	2121511-30-4
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	(2-Chloro-3,4-difluorophenyl)boronic Acid; 2-Chloro-3,4-difluorobenzeneboronic Acid; B-(2-Chloro-3,4-difluorophenyl)boronic Acid; 2121511-30-4; 2-Chloro-3,4-difluoro phenyl boronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,4-Difluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.