Description

Teclistamab is a high-purity, bispecific monoclonal antibody therapeutic agent targeting B-cell maturation antigen (BCMA) and CD3. This innovative compound is critical for advancing targeted immunotherapies in oncology research and development. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and clinical trial organizations engaged in the development of novel treatments for multiple myeloma and other hematological malignancies.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active pharmaceutical ingredient in the formulation of targeted cancer therapeutics.
• Clinical Research & Development: Essential reference standard and investigational material for preclinical and clinical studies in oncology.
• Biopharmaceutical Manufacturing: Serves as a key intermediate in the large-scale GMP production of bispecific antibody therapies.
• Mechanism of Action Studies: Used in vitro and in vivo to study T-cell redirection and tumor cell killing mechanisms.
• Assay Development & Validation: Critical component for developing bioanalytical assays (e.g., ELISA, cell-based assays) for pharmacokinetic and pharmacodynamic analysis.
• Regulatory Submissions: Supplies material for stability testing, impurity profiling, and documentation required for regulatory filings (e.g., FDA, EMA).

Basic Information

Product Name	Teclistamab
CAS No.	2119595-80-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	JNJ-64007957; JNJ 64007957; JNJ64007957; TECVAYLI; Anti-BCMA x Anti-CD3 Bispecific Antibody; BCMAxCD3 Bispecific Antibody; BCMA-CD3 Bispecific T-cell Engager
EINECS	Contact for details

Quality Control

Our Teclistamab is manufactured and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, identity confirmation, and rigorous impurity profiling to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Monomer Content (SEC-HPLC)	≥ 98.0%
Protein Content	Contact for details
Endotoxin	< 1.0 EU/mg
Biological Activity (Cell-based assay)	Contact for details
Water Content (K.F.)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.