Description

3-Methyl-3-(Methylsulfonyl)But-1-Yne is a specialized alkyne building block featuring a sulfonyl group, offering unique reactivity for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring sulfone or alkyne functionalities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its reactive alkyne group for structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in click chemistry, Sonogashira couplings, and other metal-catalyzed cross-coupling reactions to introduce functionalized alkyne units.
• Ligand and Catalyst Development: Useful for creating novel ligands for transition metal catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	3-Methyl-3-(Methylsulfonyl)But-1-Yne
CAS No.	2109226-54-0
Molecular Formula	C6H10O2S
Molecular Weight	146.21 g/mol
Synonyms	3-Methyl-3-(methylsulfonyl)-1-butyne; 3-Methyl-3-(methylsulfonyl)but-1-yne; 1-Butyne, 3-methyl-3-(methylsulfonyl)-; 3-Methylsulfonyl-3-methyl-1-butyne; 3-(Methylsulfonyl)-3-methyl-1-butyne; MSMB (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Methyl-3-(Methylsulfonyl)But-1-Yne is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.