Description

n-Methyl-N'-Methyl-o-(m-Peg4)-O'-(Propargyl-Peg4)-Cy5 is a specialized bifunctional cyanine dye derivative engineered for advanced bioconjugation and labeling applications. This compound matters for researchers and developers requiring precise, high-performance fluorescent probes with orthogonal reactive groups for site-specific modifications. It is primarily needed by professionals in biopharmaceutical R&D, diagnostic assay development, and advanced materials science who are creating next-generation imaging agents, therapeutic conjugates, and biosensors.

Application

• Bioconjugation and Probe Synthesis: Site-specific labeling of antibodies, proteins, peptides, and oligonucleotides for fluorescence imaging and detection.
• Bioorthogonal Chemistry: Utilization of the propargyl group for copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry with azide-functionalized biomolecules.
• In Vivo and In Vitro Imaging: Development of near-infrared (NIR) fluorescent probes for deep-tissue imaging, cell tracking, and molecular targeting due to the Cy5 fluorophore.
• Diagnostic Assay Development: Key component in lateral flow assays (LFAs), ELISA, and other immunoassays requiring stable, bright fluorescent signals.
• Drug Delivery & Theranostics: Conjugation to drug molecules, nanoparticles, or liposomes to create traceable delivery systems with combined therapeutic and diagnostic capabilities.
• Polymer and Materials Science: Functionalization of hydrogels, surfaces, and polymeric materials to introduce fluorescent properties for sensing and characterization.

Basic Information

Product Name	n-Methyl-N'-Methyl-o-(m-Peg4)-O'-(Propargyl-Peg4)-Cy5
CAS No.	2107273-50-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cy5-PEG4-Propargyl-PEG4-N-methylated derivative; Propargyl-PEG4-Cy5-PEG4-methyl amine; NIR Dye Alkyne-PEG4-Cy5-PEG4-methyl; Cyanine5 alkyne PEG methyl ether; Bifunctional Cy5 dye with propargyl and methyl-PEG4 linkers; 2107273-50-5; Sulfo-Cy5 alkyne PEG derivative
EINECS	Contact for details

Quality Control

Our n-Methyl-N'-Methyl-o-(m-Peg4)-O'-(Propargyl-Peg4)-Cy5 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance. Each lot undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and functional validation for labeling efficiency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep the product under an inert atmosphere (argon or nitrogen) to prevent degradation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark blue to green solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Integrity	Conforms (by NMR/assay)
Solubility	Soluble in DMSO, DMF, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.