Description

5-(5-Fluoro-2-Methoxyphenyl)-3-Methyl-1H-Pyrrole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its precise molecular structure, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), especially those targeting specific receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials.
• Biochemical Research: Employed as a tool compound in biochemical assays and pharmacological studies.
• Custom Synthesis: Available for custom chemical synthesis projects requiring high-fidelity, fluorinated heterocyclic building blocks.

Basic Information

Product Name	5-(5-Fluoro-2-Methoxyphenyl)-3-Methyl-1H-Pyrrole-2-Carboxylic Acid
CAS No.	2106575-50-0
Molecular Formula	C13H12FNO3
Molecular Weight	249.24 g/mol
Synonyms	5-(5-Fluoro-2-methoxyphenyl)-3-methyl-1H-pyrrole-2-carboxylic acid; 3-Methyl-5-(5-fluoro-2-methoxyphenyl)-1H-pyrrole-2-carboxylic acid; 1H-Pyrrole-2-carboxylic acid, 5-(5-fluoro-2-methoxyphenyl)-3-methyl-; 2106575-50-0; 5-(5-Fluoro-2-methoxyphenyl)-3-methylpyrrole-2-carboxylic acid; 3-Methyl-5-(5-fluoro-2-methoxyphenyl)pyrrole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(5-Fluoro-2-Methoxyphenyl)-3-Methyl-1H-Pyrrole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.