Description

(2R)-2-({[3,5-Bis(Trifluoromethyl)Phenyl]Carbamothioyl}Amino)-n-(2,4-Difluorophenyl)-2-Phenylacetamide is a high-purity, chiral organic compound featuring a complex molecular architecture designed for advanced research and development. This compound is of significant interest due to its potential as a key synthetic intermediate or a pharmacologically active scaffold in the discovery of new therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers working on novel bioactive molecules, particularly those targeting enzyme inhibition or receptor modulation.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, leveraging its difluorophenyl and trifluoromethyl motifs for enhanced bioactivity and environmental stability.
• Chemical Biology Probe: Acts as a tool compound for studying biological pathways, enzyme functions, or protein-protein interactions in academic and industrial research settings.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or coatings where fluorinated aromatic groups impart unique properties like chemical resistance or low surface energy.
• Medicinal Chemistry SAR Studies: Employed in structure-activity relationship (SAR) campaigns to optimize the potency, selectivity, and pharmacokinetic profile of lead drug candidates.

Basic Information

Product Name	(2R)-2-({[3,5-Bis(Trifluoromethyl)Phenyl]Carbamothioyl}Amino)-n-(2,4-Difluorophenyl)-2-Phenylacetamide
CAS No.	2101517-69-3
Molecular Formula	C24H16F8N3OS
Molecular Weight	546.47 g/mol
Synonyms	(2R)-2-[[[3,5-Bis(trifluoromethyl)phenyl]carbamothioyl]amino]-N-(2,4-difluorophenyl)-2-phenylacetamide; (R)-2-((3,5-Bis(trifluoromethyl)phenyl)thioureido)-N-(2,4-difluorophenyl)-2-phenylacetamide; 2101517-69-3; UNII-9K5F8WK3QN; 9K5F8WK3QN; SCHEMBL24823031; DTXSID70731892; AKOS040757623
EINECS	Contact for details

Quality Control

Our (2R)-2-({[3,5-Bis(Trifluoromethyl)Phenyl]Carbamothioyl}Amino)-n-(2,4-Difluorophenyl)-2-Phenylacetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with REACH and other global regulatory frameworks, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.