Description

Benzamide, 2-(Diphenylphosphino)-n-[(8α,9R)-6'-Methoxycinchonan-9-Yl]- is a sophisticated chiral organophosphorus ligand derived from cinchona alkaloid architecture. This compound is engineered to provide exceptional stereoselectivity and catalytic activity in asymmetric synthesis, a critical requirement for producing high-value enantiopure intermediates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Catalysis: As a chiral ligand for transition-metal catalyzed reactions, including hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: For the enantioselective construction of complex molecular scaffolds in API development.
• Agrochemical Research: In the synthesis of chiral active ingredients for herbicides and pesticides.
• Material Science: Development of chiral polymers and advanced functional materials with specific optical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic and organometallic chemistry.

Basic Information

Product Name	Benzamide, 2-(Diphenylphosphino)-n-[(8α,9R)-6'-Methoxycinchonan-9-Yl]-
CAS No.	2097541-17-6
Molecular Formula	C41H38N2O2P
Molecular Weight	621.73 g/mol
Synonyms	(8α,9R)-N-[2-(Diphenylphosphino)benzoyl]-6'-methoxycinchonan-9-amine; 2-(Diphenylphosphino)-N-[(8α,9R)-6'-methoxycinchonan-9-yl]benzamide; Cinchona Alkaloid-Derived Phosphine Ligand; Chiral P,N-Ligand; (8α,9R)-6'-Methoxycinchonan-9-yl 2-(Diphenylphosphino)benzamide
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral ligand adheres to stringent quality protocols. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis to ensure structural integrity and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and catalytic performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.