Description

3-(Cyclopropylcarbamoyl)-2-Fluorophenylboronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique boronic acid functional group. This compound is critical for facilitating key carbon-carbon bond-forming reactions, such as the Suzuki-Miyaura cross-coupling, enabling the efficient synthesis of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient formation of biaryl and other carbon-carbon bonds in complex organic synthesis.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for creating functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-(Cyclopropylcarbamoyl)-2-Fluorophenylboronic Acid
CAS No.	2096353-44-3
Molecular Formula	C10H11BFNO3
Molecular Weight	222.01 g/mol
Synonyms	2-Fluoro-3-(N-cyclopropylcarbamoyl)phenylboronic Acid; [2-Fluoro-3-(cyclopropylcarbamoyl)phenyl]boronic Acid; 3-(Cyclopropylaminocarbonyl)-2-fluorobenzeneboronic Acid; B-[3-(Cyclopropylcarbamoyl)-2-fluorophenyl]boronic Acid; 2-Fluoro-N-cyclopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (Pinacol Ester); CAS 2096353-44-3
EINECS	Contact for details

Quality Control

Our 3-(Cyclopropylcarbamoyl)-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.