Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl) Phenylboronic Acid is a highly functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique substitution pattern, which enables the precise construction of complex molecules through efficient cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLEDs and organic semiconductors, due to its electron-withdrawing trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a building block for creating novel bidentate ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of bioconjugates and molecular probes for target identification and validation in drug discovery.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl) Phenylboronic Acid
CAS No.	2096342-38-8
Molecular Formula	C7H4BClF4O2
Molecular Weight	241.37 g/mol
Synonyms	[3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl]boronic acid; 2-Fluoro-3-chloro-5-(trifluoromethyl)benzeneboronic acid; (3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-chloro-2-fluoro-5-(trifluoromethyl)phenyl]-; 2096342-38-8; 3-Chloro-2-fluoro-5-trifluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-Fluoro-5-(Trifluoromethyl) Phenylboronic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. All material is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.