Description

3,5-Dimethyl-2-Fluorophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and dimethyl-substituted aromatic systems.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides where the specific substitution pattern can influence biological activity.
• Material Science Research: Acts as a monomer or building block for constructing organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and tags due to the stability of the pinacol ester group under various conditions.
• Process Chemistry & Scale-up: The pinacol ester protection offers enhanced stability and handling properties, making it suitable for multi-step synthesis and larger-scale production.

Basic Information

Product Name	3,5-Dimethyl-2-Fluorophenylboronic Acid, Pinacol Ester
CAS No.	2096341-90-9
Molecular Formula	C14H20BFO2
Molecular Weight	250.12 g/mol
Synonyms	2-Fluoro-3,5-dimethylbenzeneboronic acid pinacol ester; (2-Fluoro-3,5-dimethylphenyl)boronic acid pinacol ester; 3,5-Dimethyl-2-fluorophenylboronic acid pinacol ester; Pinacol (2-fluoro-3,5-dimethylphenyl)boronate; B-(2-Fluoro-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2096341-90-9; Boronic acid, B-(2-fluoro-3,5-dimethylphenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-2-Fluorophenylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP conditions for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.