Description

5-Bromo-2-Fluoro-3-Trifluoromethylphenylboronic Acid is a high-purity, multi-functionalized boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the unique properties imparted by the halogen and trifluoromethyl substituents.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structural motifs can tune electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring this specific boronic acid scaffold.

Basic Information

Item	Details
Product Name	5-Bromo-2-Fluoro-3-Trifluoromethylphenylboronic Acid
CAS No.	2096341-70-5
Molecular Formula	C7H4BBrF4O2
Molecular Weight	286.82 g/mol
Synonyms	5-Bromo-2-fluoro-3-(trifluoromethyl)benzeneboronic acid; (5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)boronic acid; 2-Fluoro-5-bromo-3-trifluoromethylphenylboronic acid; 3-Borono-5-bromo-2-fluorobenzotrifluoride; B-(5-Bromo-2-fluoro-3-(trifluoromethyl)phenyl)boronic acid; 2096341-70-5; 5-Br-2-F-3-CF3-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-3-Trifluoromethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support development and commercial projects requiring material that meets stringent internal specifications for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive and moisture-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.